Your mission
This is an exciting fully lab-based role in which we are looking for a scientist with an immuno-oncology and pharmacology background. This role entails utilising innovative ideas for assay development to identify pathway biology of novel drug targets. Making use of a wide range of cellular, immunological, biochemical, molecular biology and functional genomic approaches, such as CRISPR/Cas9, you will validate drug targets and novel therapeutic agents including ADC’s.
Key Responsibilities:
- Design and perform experiments aimed at oncology and fibrosis target discovery and validation.
- Contribute to ongoing research on oncology and fibrosis drug discovery projects.
- Establish different robust cell-based assays aimed at target discovery, MOA validation and drug screening.
- Establish and maintain mono and co-cultures of primary cells and cell lines.
- Independently analyse, interpret, report and present results.
Your profile
Key Experience:
- Practical experience in cancer biology, immunology and pharmacology.
- Demonstrable experience in assay development, immuno-oncology and cell death biology.
- Expertise in establishing multi-colour FACS panels for analysis of complex cell populations is an advantage.
- Hands-on experience of key immunological and molecular biology techniques including but not limited to RNA/DNA extraction, qRT-PCR, ELISA/Luminex/MSD, western blotting.
- Prior working experience in the biotech/pharma industry performing laboratory research would be an advantage.
Qualifications and Competencies:
- PhD in Biomedical sciences, Immunology, Biochemistry, Biotechnology or related discipline or MSc plus 3 years practical experience in cellular or molecular biology, molecular pharmacology or cancer biology with a focus on immuno-oncology.
- Prior working experience in the biotech/pharma industry performing laboratory research would be an advantage.
- Able to plan, execute and critically assess experiments independently.
- Excellent time-management skills and ability to work to set deadlines.
- Work well within a team and in a matrix environment.
About us
We are pioneering the way to significantly improve the lives of fibrosis and solid tumour patients and their families. Through our unique understanding of the extra-cellular matrix (ECM), and our world-class technology and approach, we are unlocking insights and enabling the generation of new, advanced therapeutics.
At Engitix, relationships are the foundation of accomplishment.
We are one team working together in service of our mission to significantly improve the lives of fibrosis and solid tumour patients and their families. We care deeply about what we do and the impact we will have. Our dedication to be passionate, committed and respectful is at the heart of how we operate. It’s our DNA.
